Dr IELiapakis presented his PhD thesis on "The influence of leptin in neovascularization and survival of random skin flaps. Experimental study in rats" at the Medical School of Democritus University of Thrace at Alexandrouplois, Greece and awarded with honors. As part of his PhD thesis published the following studies in international journals:

Liapakis IE, Anagnostoulis S, Karayiannakis AJ, Korkolis D, Lambropoulou M, Arnaud E, Simopoulos C. "Recombinant leptin administration improves early angiogenesis in full-thickness skin flaps: an experimental study". In vivo 2008; 22: 247-252

Liapakis IE, Anagnostoulis S, Karayiannakis AJ, Korkolis D, Lambropoulou M, Matarasso A, Simopoulos C. «Burn wound angiogenesis is increased by exogenously administered recombinant leptin in rats», Acta Cir Bras 2008; 23(2): 118-124

Liapakis IE, Anagnostoulis S, Karayannakis AJ, Korkolis DP, Lambropoulou M, Anastakis DP, Simopoulos CE. «Exogenously administered leptin increases early incisional wound angiogenesis in an experimental model», In vivo 2007; 21: 797- 802

It is his second PhD thesis because he awarded at the University of Crete Medical School in 2004 with honors for his work on “Pharmacokinetics and pharmacodynamics of newer macrolides and quinolones in the treatment of empyema in rabbits”.