Neuromodulators are purified proteins produced by the Clostridium Botulinum bacteria. It has been used for wrinkle therapy since the early 1990's with no serious side effects documented. A small amount of Botulinum toxin is injected into the muscles that are responsible for creating wrinkles or undesirable facial muscle effects. This treatment is quick and somebody can repeat the treatment 2-3times/year (the result may stay longer if it's combined with 50mg tablets of zinc 1 week before and after the treatment).

The neuromodulators temporarily inactivates the muscles that produce wrinkles, thereby causing lines to disappear or diminish dramatically. It usually takes a few days after the injection to notice the wrinkle smoothing effect.

Some of the common areas treated with botox include crow's feet, frown lines, laugh lines, and forehead wrinkles. The neuromodulators can also be injected to weaken the muscles responsible for a "gummy smile", which can improve this appearance dramatically. Injections into muscles that lower the eyebrow or corners of the mouth can produce a form of temporary brow lift or lip lift. The last improvement is the micro-injections intradermally: tiny amounts of highly diluted injections decrease the sebaceous/sweat glands secretions, relax the platysma muscle and eliminate the small wrinkles around the face (Wu WT. Micro......Personal Technique and Its Clinical Effects. PRS 2015 Nov;136(5 Suppl):92S-100S). New uses for New uses for neuromodulators include reduction in sweating of hands (hyperhidrosia) and relief of headaches.